A clinically driven characterization of pathological and non-pathological brain aging in the Rhesus Macaque model: Impact of caloric restriction Public Deposited

This dissertation focuses on brain aging and neurodegeneration, specifically in the context of healthy brain aging versus Alzheimer’s disease (AD). To study these processes, a translational model of human aging is necessitated; therefore, this dissertation will focus on the rhesus macaque’s utility in modeling clinically normative and pathological brain aging. Protein-level consequences of central nervous system (CNS) aging in monkeys will be experimentally explored and discussed in comparison to concomitant clinical phenotypes.


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  • Stonebarger.Gail.2022.pdf
  • https://doi.org/10.6083/zs25x9220
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  • 2022
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