Dengue virus and the suppression of the cellular innate immune response: antiviral microRNAs as a tool for probing host-virus interactions Public Deposited

This dissertation describes the implementation of a technique for using cellular miRNAs as tools for the discovery of virus-host interactions. With this methodology, I discovered a new function for the UPR during DENV2, namely inhibition of innate immune signaling, as well as identifying a miRNA that impedes flavivirus infection in spite of failure to enhance cellular immunity.


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  • Murphy.Ashleigh.2017.pdf
  • https://doi.org/10.6083/m4sx6csd
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  • 2017
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