Dr. Mary Stenzel-Poore is an outstanding figure in the field of neuroimmunology as well as within OHSU’s history. Her lab’s work is centered on neuroprotection and immunotherapy research that seeks to prevent the brain against injury in a stroke. Dr. Stenzel-Poore is Chief of Research Operations at the Knight Cancer Institute and Professor of Molecular Microbiology and Immunology. This interview traces her experiences at OHSU as a graduate student, a postdoc, a faculty member, department chair, and associate dean, in addition to her current roles. Dr. Stenzel-Poore discusses her unique perspective of the development of OHSU in tandem with her own growth within the institution. The interview captures a variety of topics, from personal experience to administrative insight, as well as commentary on themes such as women in health and science, and progress in times of financial unrest.